| 2567622 |
Griffiths SA, Manson MM: Rat liver gamma glutamyl transpeptidase mRNA differs in the 5' untranslated sequence from the corresponding kidney mRNA. Cancer Lett. 1989 Jul 1;46(1):69-74.
A clone containing the entire protein-coding region of gamma glutamyl transpeptidase (GGT) from ethoxyquin- (EQ) treated rat liver has been isolated from a cDNA library. DNA sequence analysis showed that the protein-coding and 3' untranslated regions are almost identical to rat kidney GGT, but the sequences differ in the 5' untranslated region. Southern blot data suggest a single gene for GGT in the rat, hence the different mRNAs may originate by differential transcriptional and/or posttranscriptional processing. |
7(0,0,1,2) |