Protein Information

ID 1769
Name melanoma associated antigen
Synonyms CLL associated antigen KW 1; CLL associated antigen KW 1 splice variant 1; CLL associated antigen KW 1 splice variant 2; Melanoma associated antigen; CLL associated antigen KW 1 splice variant 1s; CLL associated antigen KW 1 splice variant 2s; Melanoma associated antigens

Compound Information

ID 864
Name MAA
CAS methylarsonic acid

Reference

PubMed Abstract RScore(About this table)
3040633 Wang TS, NG AK, Alsedairy S, Fawwaz RA, Hardy MA, Alderson PO: A method for direct quantification of the amount of DTPA in 111In monoclonal antibody preparations. Int J Rad Appl Instrum A. 1987;38(4):315-9.
The bicyclic anhydride of DTPA-1-14C (BADTPA-1-14C) was synthesized and reacted with an antibody to human melanoma associated antigen (MAA) and with one to human class II major histocompatibility complex antigen (HLA-DR). DTPA-1-C incorporation per mole of anti MAA at molar ratios of 1:1 to 200:1 ranged from 0.5 to 25, while immunoreactivity ranged from 49 to 9%. With antibody to HLA-DR, results were similar. Anti MAA, but not anti HLA-DR, demonstrated polymerization upon conjugation. BADTPA-1-14C provides a convenient and accurate method for measuring the amount of DTPA in monoclonal antibody preparations and its effect on immunoreactivity.		 1(0,0,0,1)