| 3889169 |
Ernstoff MS, Duray P, Stenn K, Kirkwood JM: Antigenic phenotype of pigment cell lesions: a study of melanoma, its precursor lesions and heterogeneity in metastatic melanoma. J Invest Dermatol. 1985 May;84(5):430-2.
Expression of surface antigens on cells comprising malignant, dysplastic, and benign pigment cell lesions has been evaluated in situ using an avidin-biotin immunohistologic technique. We have demonstrated expression of HLA-DR, beta 2-microglobulin, and 2 melanoma-associated antigens (MAA) in a range of benign and malignant lesion, and have confirmed the close association of HLA-DR and MAA on malignant lesions. In addition, 5 subcutaneous lesions removed at the same time from one individual were evaluated. Clinical and histologic appearance differed among lesions although the antigenic patterns were similar. |
6(0,0,1,1) |