Protein Information

ID 1729
Name acetolactate synthase
Synonyms Acetolactate synthase; OR10B1P

Compound Information

ID 959
Name imazapyr
CAS

Reference

PubMed Abstract RScore(About this table)
12476991 Aviv D, Amsellem Z, Gressel J: Transformation of carrots with mutant acetolactate synthase for Orobanche (broomrape) control. Pest Manag Sci. 2002 Dec;58(12):1187-93.
Parasitic Orobanche spp are major constraints to vegetable crop production in the Mediterranean basin (to eastern Europe) and in localized places in India, China and the USA. Transgenic target-site herbicide resistance (eg, to acetolactate synthase inhibitors) allows for movement of unmetabolized herbicide through the crop to the photosynthate sink in the parasite, as well as through the soil. We report the successful engineering of a mutant acetolactate synthase (ALS) gene into carrot, allowing control of broomrape already in heterozygotes of the first back-crossed generation, by imazapyr, an imidazolinone ALS inhibitor. It is expected that homozygotes will have higher levels of resistance.
33(0,1,1,3)