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Cao J, Doyle RJ: Fluoride modifies adhesion of Streptococcus pyogenes. FEMS Immunol Med Microbiol. 2002 Jan 14;32(2):175-7. Streptococcus pyogenes grown in the presence of subinhibitory concentrations of sodium fluoride had a diminished ability, compared to control cells, to adhere to buccal cells, collagen, fibronectin, and laminin. In addition, sodium fluoride was a competitive inhibitor of streptococcal adhesion to collagen and fibronectin, but not laminin. It is suggested that sodium fluoride may be useful in therapy or prophylaxis in infections involving group A streptococci. |
6(0,0,1,1) |