Protein Information

ID 2455
Name monocyte chemotactic protein 1
Synonyms CCL 2; MCAF; CCL2; GDCF 2; GDCF 2 HC11; GDCF2; HC11; HSMCR30…

Compound Information

ID 1390
Name acrylonitrile
CAS 2-propenenitrile

Reference

PubMed Abstract RScore(About this table)
19354228 Moss RA, Zhang M, Krogh-Jespersen K: Latent nucleophilicity of dichlorocarbene. Org Lett. 2009 May 7;11(9):1947-50.
Rate constants and activation parameters are reported for additions of CCl (2) to methyl acrylate, acrylonitrile, and alpha-chloroacrylonitrile. The results reveal latent nucleophilicity in the addition of CCl (2) to alpha-chloroacrylonitrile, a conclusion supported by theoretical studies of the cyclopropanation reaction transition state.
32(0,1,1,2)