Protein Information

ID 42
Name lactate dehydrogenase (protein family or complex)
Synonyms LDH; lactate dehydrogenase; lactate dehydrogenases

Compound Information

ID 1391
Name carbon disulfide
CAS carbon disulfide

Reference

PubMed Abstract RScore(About this table)
605628 El-Dessoukey EA, Awadallah R, Mikhail TH: Serum enzyme changes associated with carbon disulfide hepatotoxicity in experimental animals. Z Ernahrungswiss. 1977 Dec;16(4):262-7.
Investigations were performed to evaluate the activities of serum glutamic oxalacetic and glutamic pyruvic transaminases, alkaline phosphatase and lactate-dehydrogenase enzymes in rats intoxicated by different doses of carbon disulfide. Serum GOT and GPT activities were elevated which may be due to CS2 effect on cell membrane permeability. Serum-alkaline-phosphatase activity showed also increment, which was again attributed to the liver affection. A significant rise in serum-lactate-dehydrogenase activity which was referred to be as a result of muscle-lactate dehydrogenase release into the blood circulation.
7(0,0,1,2)