| 994023 |
Levine TE: Effects of carbon disulfide and FLA-63 on operant behavior in pigeons. J Pharmacol Exp Ther. 1976 Dec;199(3):669-78.
Carbon disulfide (CS2) and FLA-63 [bis (4-methyl-1-homopiperazinylthiocarbonyl) disulfide] were studied in pigeons working on a differential-reinforcement-of low-rates or a multiple fixed-interval fixed-ratio schedule of food reinforcement. Response rate on both schedules decreased after 8-hour exposures to CS2 (2 mg/1) of administration of FLA-63 (40 and 80 mg/kg). The effects of two successive 8-hour exposures to CS2 were cumulative and ten successive 4-hour exposures produced changes in differential-reinforcement-of-low-rates performance resembling those following acute exposure. Fixed-interval performance was disrupted by exposures to CS2 and doses of FLA-63 that left fixed-ratio performance intact. |
9(0,0,1,4) |