Protein Information

ID 109
Name CS2
Synonyms Alcagamma; CLSTN 2; CLSTN2; CS2; CSTN 2; CSTN2; Calsyntenin 2; Calsyntenin 2 precursor…

Compound Information

ID 1391
Name carbon disulfide
CAS carbon disulfide

Reference

PubMed Abstract RScore(About this table)
8937537 Chu CC, Huang CC, Chu NS, Wu TN: Carbon disulfide induced polyneuropathy: sural nerve pathology, electrophysiology, and clinical correlation. Pol Tyg Lek. 1989 May 22-29;44(21-22):492-5
We report the clinical features, electrophysiological studies, sural nerve pathology and recovery course of carbon disulfide-(CS2) induced polyneuropathy in a 48-year-old man who worked in a viscose rayon plant. Sural nerve biopsy 2 years later still showed degeneration of both axon and myelin with a predominant loss of large myelinated fibers and remyelination. Electrophysiologic studies revealed mixed axonal and demyelinating polyneuropathy. To our knowledge, this is the first human report of sural nerve pathology in the recovery stage due to CS2 intoxication. After diagnosis, the patient was removed from the toxic environment. In the following three years, he showed part recovery predominantly in motor function compatible with the serial nerve conduction studies. We conclude that CS2 polyneuropathy may partly recover years after cessation of exposure.
8(0,0,1,3)