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Candura F, Franco G, Malamani T, Piazza A: Altered glucose tolerance in carbon disulfide exposed workers. Acta Diabetol Lat. 1979 Jul-Sep;16(3):259-63.
Oral cortisone glucose tolerance tests were performed in 66 CS2-exposed workers and in 66 individually matched control subjects. Results indicate a higher and significant (p less than 0.001) prevalence of latent diabetes in the CS2-exposed group (72.7%) as compared with the control group (16.7%), and the existence of a positive and significant (p less than 0.001) correlation between blood glucose values and exposure index. Possible mechanisms of action involving zinc metabolism and pyridoxine metabolism are discussed. |
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