| 7277852 |
Onodera M, Sakurai H, Toyama T: [The protective effect of vitamin E on the hepatotoxic effects of CS2 in male albino rats of Wistar strain (author's transl)]. Sangyo Igaku. 1981 May;23(3):300-4.
In Vitamin E deficient rats, which had received an oral CS2 administration of the dose at 1 mg/kg following a peritoneal injection of phenobarbital sodium and a fasting period of 24 hours, histopathological changes such as vacuolar degeneration and fatty infiltration of the liver were observed along with the increases in liver weight and liver/body weight ratio. On the other hand, no such effects could be found in Vitamin E supplemented rats which otherwise received the same treatment as the Vitamin E deficient group. |
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