| 19441727 |
Satanovskaia VI, Pron'ko PS, Gaishmanova AV, Miskevich DA: [Effects of panthenol and carnitine on aldehyde metabolic enzymes in rats with tetrachloromethane-induced liver injury]. Eksp Klin Farmakol. 2009 Mar-Apr;72(2):39-40.
Tetrachloromethane (2 g/kg, intragastric) produced a decrease in the activity of NAD- and NADH- dependent aldehyde dehydrogenases with high Km for aldehydes in rat liver. Panthenol and L-carnitine administered separately normalized the activity of aldehyde dehydrogenases, while a combination of the drugs did not produce any significant effect. |
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