| 16027843 |
Filimonov PN, Sukhenko TG, Gavrilova NI, Shkurupii VA: Effect of IFN-alpha on CC1 4-induced fibrosis of the liver and immune status in mice of different age. Bull Exp Biol Med. 2005 Mar;139(3):324-7.
In young, adult, and old mice fibrosis was induced by administration of CC1 (4) and treated with IFN-alpha; liver fibrosis was evaluated by morphometry of argyrophilic fibers, immune status by the splenocyte proliferative response. minimum immunosuppression and maximum antifibrotic effect were observed in young mice, while adult mice exhibited pronounced immunotoxicity and weak response to interferon therapy. |
1(0,0,0,1) |