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Satturwar PM, Fulzele SV, Joshi SB, Dorle AK: Hepatoprotective activity of Haridradi ghrita on carbon tetrachloride-induced liver damage in rats. J Ethnopharmacol. 2008 Mar 28;116(3):539-46. Epub 2008 Jan 20. Haridradi ghrita, a ghee based polyherbal formulation, (50, 100, 200 and 300 mg/kg) significantly lowered marker enzymes (SGPT, SGOT, ALP) and bilirubin in serum and liver peroxide, superoxide dismutase and catalase in liver homogenate following CCl4 (0.7 ml/kg, ip) toxicity. The protective effect was further supported by reversal of CCl4 induced histological changes. The results demonstrate significant hepatoprotective action of H. ghrita in CCl4 damaged rats. |
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