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Ansari GA, Singh SV, Gan JC, Awasthi YC: Human erythrocyte glutathione S-transferase: a possible marker of chemical exposure. Toxicol Lett. 1987 Jun;37(1):57-62.
We have explored the possibility of using glutathione S-transferase (GST) as a biological marker of chemical exposure. All the model compounds tested in the present study (acrolein, propylene oxide, styrene oxide, ethylene dibromide and ethylene dichloride) showed a dose-dependent inactivation of erythrocyte GST in situ as well as the inhibition of purified erythrocyte GST. |
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