Protein Information

ID 496
Name Cytochrome c oxidase (protein family or complex)
Synonyms COX; cytochrome c oxidase; cytochrome c oxidases

Compound Information

ID 1576
Name acephate
CAS

Reference

PubMed Abstract RScore(About this table)
6312637 Ando M, Wakamatsu K: Difference absorption spectrum of cytochrome c oxidase in the presence of acephate (N-acetyl O,S-dimethyl thiophosphoramide). Toxicol Lett. 1983 Jun;17(1-2):85-8.
The alpha-peak in the difference spectrum between reduced cytochrome c oxidase (cytochrome a and a3) plus acephate (pH 9.5) and oxidized enzyme, shifted from 605 nm to 592 nm. The difference spectrum between reduced cytochrome c oxidase plus acephate (pH 9.5) and the reduced enzyme showed that the alpha and gamma peaks shifted to 592 nm and 432 nm, respectively. The effect of acephate on the spectrum of the reduced cytochrome c oxidase is similar to that of carbon monoxide.
68(0,2,3,3)