Protein Information

ID 3117
Name true cholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

ID 1493
Name phosphamidon
CAS 2-chloro-3-(diethylamino)-1-methyl-3-oxo-1-propenyl dimethyl phosphate

Reference

PubMed Abstract RScore(About this table)
7927563 Datta C, Gupta J, Sengupta D: Interaction of organophosphorus insecticides phosphamidon & malathion on lipid profile & acetylcholinesterase activity in human erythrocyte membrane. Indian J Med Res. 1994 Aug;100:87-9.
The organophosphorus insecticides phosphamidon and malathion were found to inhibit the activity of human acetylcholinesterase in vitro, in the human erythrocyte membrane. Lineweaver-Burk analysis indicated that the insecticide induced inhibition of acetylcholinesterase activity was uncompetitive in nature. The total lipid, cholesterol and phospholipid contents of erythrocyte membranes were reduced following phosphamidon and technical malathion treatment, while the level of lipid peroxidation was raised following malathion treatment.
113(1,2,2,3)