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Stillion JR, Ritt M: Renal secondary hyperparathyroidism. . Compend Contin Educ Vet. 2009;31(6):E1-E11.
Parathyroid gland hyperplasia and subsequent hyperparathyroidism can occur secondary to chronic renal failure in dogs, resulting in significant alterations in calcium metabolism. Renal secondary hyperparathyroidism is a complex, multifactorial syndrome that involves changes in circulating levels of calcium, parathyroid hormone (PTH), phosphorus, and 1,25-dihydroxycholecalciferol (calcitriol). An increased PTH level can have many deleterious effects. Dietary phosphorus restriction, intestinal phosphate binders, and calcitriol supplementation may slow the progression of renal disease and decrease PTH concentrations in animals with secondary hyperparathyroidism. |
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