| 19436945 |
Ohta H, Kuroda T, Onoe Y, Orito S, Ohara M, Kume M, Harada A, Tsugawa N, Okano T, Sasaki S: The impact of lifestyle factors on serum 25-hydroxyvitamin D levels: a cross-sectional study in Japanese women aged 19-25 years. J Bone Miner Metab. 2009;27(6):682-8. Epub 2009 May 14.
Insufficient levels of serum 25-hydroxyvitamin D [25 (OH) D] lead to low bone mineral density (BMD) by increasing serum levels of intact parathyroid hormone (PTH), and are associated with a high mortality rate. Therefore, the 25 (OH) D level is used as an indicator of frailty in older persons. To obtain higher serum 25 (OH) D levels, management of lifestyle habits and nutrient intake is important beginning in a person's younger years. This study evaluated the degree of association between serum 25 (OH) D concentrations and lifestyle factors in young Japanese women. A cohort study was conducted from December 2003, and the survey was finished by February 2004. The subjects were 274 Japanese women aged 19-25 years old. The parameters evaluated in these subjects included: (1) serum concentrations of 25 (OH) D, intact PTH, calcium, and phosphorus; (2) BMD in the lumbar spine and hip; and (3) lifestyle factors (nutrient intake, physical activity, and duration of sunlight exposure). The serum 25 (OH) D level was negatively associated with the intact PTH level (Spearman; r = -0.17, P = 0.006). The BMD was significantly higher in the high 25 (OH) D and low intact PTH group than the other group (P < 0.05). The serum 25 (OH) D level was significantly correlated with daily intake of dietary vitamin D (r = 0.20, P = 0.001), the mean number of steps taken per day (r = 0.16, P = 0.010) and the mean time spent in sedentary activity (r = -0.14, P = 0.018) among the lifestyle factors evaluated. Multiple regression analysis showed the degree of association between lifestyle factors and serum 25 (OH) D to be small (R (2) = 0.084). Daily intake of dietary vitamin D and daily walking may be useful for increasing the serum 25 (OH) D level in young Japanese women. |
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