| 19432210 |
Pauk VV, Nasibullin TR, Tuktarova IA, Zueva LP, Mustafina OE: [Antioxidant gene polymorphism and longevity] . Adv Gerontol. 2008;21(4):593-5.
On sample of 1534 ethnic Tatars catalase (CAT, -262C/T), glutathione peroxidase 1 (GPX1, L198P) and methionine sulfoxide reductase A (MSRA, -402C/T) gene polymorphisms in connection with lifespan were studied. On each separate polymorphic marker nonlinear character of alleles and genotypes frequencies changes with age was revealed. Combinations of genotypes CAT*C/*T-GPX1 *L/*L were significant for elderly and senile age. |
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