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Klucinski P, Kossmann S, Friedek D: Release of interleukin-1 beta from peripheral blood monocytes and its concentration in the blood serum of the workers employed at the production of chlorfenvinphos. Przegl Lek. 1997;54(10):716-8.
Our earlier investigations of people exposed to chlorfenvinphos revealed obstructive impairment of pulmonary function and changes in collagen metabolism. In order to evaluate the role of interleukin-1 beta in the development of these changes the serum interleukin-1 beta concentration and the ability of spontaneous and LPS stimulated production of interleukin-1 beta by monocytes were determined in 25 males aged 33-54 years and employed at the department producing chlorfenvinphos (its air concentration did not exceed permissible levels). Higher spontaneous production of interleukin-1 beta was found; the remaining parameters did not differ significantly as compared to the control group of 23 healthy males. |
31(0,1,1,1) |