Protein Information

ID 1892
Name VKORC1
Synonyms Vitamin K epoxide reductase; IMAGE3455200; MST134; MST576; MSTP134; MSTP576; Phylloquinone epoxide reductase; UNQ308…

Compound Information

ID 1766
Name bromadiolone
CAS

Reference

PubMed Abstract RScore(About this table)
16933704 Kupper J, Grobosch T, Kistler R, Sydler T, Naegeli H: [Bromadiolone poisoning in foxes] . Schweiz Arch Tierheilkd. 2006 Aug;148(8):405-8.
Bromadiolone is an anticoagulant rodenticide that inhibits the reactivation of vitamin K1 by the enzyme vitamin K1-epoxide reductase. The present case report originated from the application of bromadiolone against water voles (Arvicola terrestris) in northeastern Switzerland. At least 40 foxes (Vulpes vulpes) were found dead after the inappropriate use of a bait that contained 0.02 % bromadiolone. Anticoagulant rodenticide poisoning was suspected on the basis of the postmortem examination and subsequently confirmed by the detection ofbromadiolone both in the blood and in samples from thoracic and abdominal fluids.
81(1,1,1,1)