Protein Information

ID 179
Name prothrombin
Synonyms Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin…

Compound Information

ID 1771
Name difenacoum
CAS

Reference

PubMed Abstract RScore(About this table)
2330467 Nighoghossian N, Ruel JH, Ffrench P, Froment JC, Trouillas P: [Cervicodorsal subdural hematoma caused by coumarinic rodenticide poisoning]. Rev Neurol. 1990;146(3):221-3.
A 59-year old man developed subacute tetraparesis following severe sudden neck pain. MRI showed a subdural cervical hematoma. Prothrombin complex activity was low. An unusual coagulopathy after rodenticides exposure was found. Diphenacoum, an effective antagonist of vitamin K1, was present in the patients plasma. Specific medical management led to a complete recovery. Follow-up MRI seventy days later confirmed the complete disappearance of the hematoma.
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