| 20143730 |
Lajmanovich RC, Attademo AM, Peltzer PM, Junges CM: Inhibition and recovery of cholinesterases in Odontophrynus americanus tadpoles exposed to fenitrothion. J Environ Biol. 2009 Sep;30(5 Suppl):923-6.
We determined the levels of brain acetylcholinesterase (AChE) and tail butyrylcholinesterase (BChE) activities in tadpoles of Odontophrynus americanus exposed to a commercial formulation of fenitrothion. The mean brain AChE activities in the controls tadpoles varied from 6.91 to 6.39 micromol min (-1) mg (-1) protein, whereas tail BChE activities ranged among 0.26 to 0.17 micromol min (-1) mg (-1) protein; the two sublethal concentrations of fenitrothion assayed produced AChE and BChE inhibition (p < 0.01). Brain AChE recovered a substantial level of activity with a maximum of 93.2%; after the transference of tadpoles to a free-pesticide solution, whereas tail BChE recovery showed a smaller increase (39%) in the activity at 168 hr after to transference to clear water. According with our results, we suggest that tadpole's tail BChE presents higher sensibility than brain AChE. |
37(0,1,2,2) |