Protein Information

ID 88
Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

ID 208
Name demeton-S
CAS

Reference

PubMed Abstract RScore(About this table)
7237776 Lewis PJ, Lowing RK, Gompertz D: Automated discrete kinetic method for erythrocyte acetylcholinesterase and plasma cholinesterase. Clin Chem. 1981 Jun;27(6):926-9.
We describe an automated kinetic method for erythrocyte acetylcholinesterase (EC 3.1.1.7) and plasma cholinesterase (EC 3.1.1.8) based on Ellman's colorimetric method. Quinidine sulfate is used as an inhibitor of plasma cholinesterase during the measurement of erythrocyte acetylcholinesterase activity, obviating the need for washing the erythrocytes before lysis. Results by this method are compared with those obtained by the electrometric delta pH method of Michel. To emphasize the need for measuring both erythrocyte acetylcholinesterase and plasma cholinesterase activity in workers exposed to organophosphate pesticides, we present a study of serial activities of both enzymes in a person accidentally exposed to demeton-S-methyl.
9(0,0,1,4)