| 3630482 |
Potemkina EE, Galkina LV, Khrometskaia TM, Krylova EE, Mamaeva TA: [Possibility of decreasing the anticomplement activity of human immunoglobulin preparations via chemical modification]. Zh Mikrobiol Epidemiol Immunobiol. 1987 Jun;(6):54-7.
The physicochemical and immunological properties of the experimental batches of the preparations of placental immunoglobulin, obtained by some methods of chemical modification of the molecule of IgG, have been studied. The possibility of abolishing the anticomplement properties of the preparations treated with sulfitolytic agents manufactured in the USSR has been shown. The optimum conditions permitting the production of the preparation with faintly pronounced anticomplement properties and the full monomer structure of its molecule have been established. |
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