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Nakata M, Yuasa T, Takahashi Y, Ishida S: CDPK1, a calcium-dependent protein kinase, regulates transcriptional activator RSG in response to gibberellins. Plant Signal Behav. 2009 May;4(5):372-4. Epub 2009 May 19.
The homeostasis of gibberellins (GAs) is maintained by negative-feedback regulation in plant cells. REPRESSION OF SHOOT GROWTH (RSG) is a transcriptional activator with a basic Leu zipper domain suggested to contribute GA feedback regulation by the transcriptional regulation of genes encoding GA biosynthetic enzymes. The 14-3-3 signaling proteins negatively regulate RSG by sequestering it in the cytoplasm in response to GAs. The phosphorylation on Ser-114 of RSG is essential for 14-3-3 binding of RSG; however, the kinase that catalyzes the reaction is unknown. Recently a Ca (2+)-dependent protein kinase (CDPK) was identified as an RSG kinase that promotes 14-3-3 binding of RSG by phosphorylation of the Ser-114 of RSG. Our results suggest that CDPK decodes the Ca (2+) signal produced by GAs and regulates the intracellular localization of RSG in plant cells. |
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