Protein Information

ID 33
Name ATPase
Synonyms ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1…

Compound Information

ID 189
Name monocrotophos
CAS

Reference

PubMed Abstract RScore(About this table)
15031937 Wei X, Ru S, Jiang M, Li Y: [Effect of monocrotophos on Na+/K (+)-ATPase activity and ultramicrostructure of Sciaenops ocellatus branchiae]. Ying Yong Sheng Tai Xue Bao. 2003 Dec;14(12):2289-94.
The exposure of Sciaenops ocellatus to monocrotophos at its concentration of 0.25, 0.5, 1.0 or 2.0 mg L-1 for 4 days demonstrated that under the stress of low concentration (0.25 mg.L-1) monocrotophos, the chloride cells of branchiae proliferated, accompanied with the increase of Na+/K (+)-ATPase activity, while under high concentrations of monocrotophos, the damage of gill was much heavier, and the Na+/K (+)-ATPase activity also decreased. The damage in gill under sublethal monocrotophos exposure included hypertrophy and edema, and thus, the lamellar epithelium became thick and lifting, and the lamellae were bulbing or fusing. The ultramicrostructural changes of the gill of the exposure fish were the swollen and even rupture of rER, mitochondria, microtubule and nuclear membrane.
12(0,0,2,2)