18831371 |
Ramaneswari K, Rao LM: Influence of endosulfan and monocrotophos exposure on the activity of NADPH cytochrome C reductase (NCCR) of Labeo rohita (Ham). J Environ Biol. 2008 Mar;29(2):183-5. The response of NADPH cytochrome C reductase (NCCR) activity in liver of Labeo rohita fish exposed to the pesticides, 0.25 microgl (-1) endosulfan and 2 mg/l monocrotophos was studied. In terms of specific enzyme activity (mU/mg protein) a significant level of NCCR was observed in the liver tissues of Labeo rohita exposed to the pesticides, when compared to the control fish (2.460 mU/mg protein). Increase of NCCR activity was more in the liver of the fish exposed to monocrotophos (4.595 mU/mg protein) than those exposed to endosulfan (2.850 mU/mg protein). The results demonstrate that the pesticides, endosulfan and monocrotophos, interfere with NADPH dependent monoxygenase mechanism and are effective inducers of NADPH cytochrome C reductase. The activity of NCCR in the liver tissue of Labeo rohita may serve as a useful tool for monitoring aquatic pollution. |
93(1,1,3,3) |