Protein Information

ID 593
Name 5 HT1A
Synonyms 5 HT 1A; serotonin receptor; 5 HT1A; 5 hydroxytryptamine (serotonin) receptor 1A; 5 hydroxytryptamine 1A receptor; 5HT1A; ADRB2RL1; ADRBRL 1…

Compound Information

ID 1819
Name piperazine
CAS piperazine

Reference

PubMed Abstract RScore(About this table)
11327592 Sabb AL, Vogel RL, Kelly MG, Palmer Y, Smith DL, Andree TH, Schechter LE: 1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT1A receptors. Bioorg Med Chem Lett. 2001 Apr 23;11(8):1069-71.
Amino acid derivatives of 1,2,5-thiadiazol-3-yl-piperazine related to (+)-WAY-100135 and WAY-100635 are potent 5-HT1A receptor agonists and antagonists, which have selective affinity for 5-HT1A receptors versus alpha1 and dopamine (D2, D3, and D4) receptors.
82(1,1,1,2)