phospholipase A2

General Information (Source: NCBI Gene,UniProt)

Text mining Term phospholipase A2
UniProt ID PA21B_RAT
Name Group IB phospholipase A2
Phospholipase A2
Phosphatidylcholine 2-acylhydrolase 1B
Gene Names Pla2g1b
Taxonomy Rattus norvegicus

General annotation

Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides.
Subcellular location Secreted.

Gene Ontology

GO:0045740 positive regulation of DNA replication BP
GO:0032869 cellular response to insulin stimulus BP
GO:0043498 cell surface binding MF
GO:0030141 secretory granule CC
GO:0005102 receptor binding MF
GO:0047498 calcium-dependent phospholipase A2 activity MF
GO:0015758 glucose transport BP
GO:0006633 fatty acid biosynthetic process BP

Sequence

>gi|13928792|ref|NP_113773.1| phospholipase A2 precursor [Rattus norvegicus]
MKLLLLAALLTAGVTAHSISTRAVWQFRNMIKCTIPGSDPLREYNNYGCYCGLGGSGTPVDDLDRCCQTH
DHCYNQAKKLESCKFLIDNPYTNTYSYKCSGNVITCSDKNNDCESFICNCDRQAAICFSKVPYNKEYKDL
DTKKHC

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Database Cross Reference

Ensembl Gene ENSRNOT00000001525
UniGene Rn.4283
PDB
RefSeq NP_113773.1
Pfam PF00068