| Text mining Term | NR3A |
|---|---|
| UniProt ID | NMD3A_RAT |
| Name |
Glutamate [NMDA] receptor subunit 3A NMDAR-L Glutamate receptor chi-1 NMDAR-L1 NR3A N-methyl-D-aspartate receptor subtype 3A N-methyl-D-aspartate receptor NMDAR3A |
| Gene Names |
Grin3a
|
| Taxonomy | Rattus norvegicus |
| Function |
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May also play a role in PPP2CB-NMDAR mediated signaling mechanism. |
|---|---|
| Subcellular location |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Enriched in post-synaptic plasma membrane and post-synaptic densities. Requires the presence of GRIN1 to be targeted at the plasma membrane. |
| GO:0035235 | ionotropic glutamate receptor signaling pathway | BP |
| GO:0048511 | rhythmic process | BP |
| GO:0004972 | N-methyl-D-aspartate selective glutamate receptor activity | MF |
| GO:0005234 | extracellular-glutamate-gated ion channel activity | MF |
| GO:0051721 | protein phosphatase 2A binding | MF |
| GO:0045211 | postsynaptic membrane | CC |
| GO:0016594 | glycine binding | MF |
| GO:0042165 | neurotransmitter binding | MF |
| GO:0030288 | outer membrane-bounded periplasmic space | CC |
| GO:0017146 | N-methyl-D-aspartate selective glutamate receptor complex | CC |
| GO:0014069 | postsynaptic density | CC |
| GO:0030054 | cell junction | CC |
>gi|310703673|ref|NP_612555.1| glutamate [NMDA] receptor subunit 3A isoform 1 precursor [Rattus norvegicus] MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQE GGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAETLWPRDALLFAVENLNRVEG LLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELD LVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFL LLTENNSKFHLESVINITANLSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPP ELHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCM DVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTRLGSWQGGRIV MDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSS LHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVT SFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSP FGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVG EKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLD AFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKV VPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLLPRIKNKSKLQYWLHTSQRFH RALNTSFVEEKQPRSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNLGPQQLMVWNTSNLSHDNQRKYIFN DEEGQNQLGTQAHQDIPLPQRRRELPASLTTNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRK TELEEYQKTNRTCES |
| Ensembl Gene |
ENSRNOT00000007957 |
|---|---|
| UniGene |
Rn.180226 |
| PDB |
2RC9 2RC8 2RC7 |
| RefSeq |
NP_001185512.1 NP_612555.1 |
| Pfam |
PF00497 PF00060 PF01094 |