estrogen receptor

General Information (Source: NCBI Gene,UniProt)

Text mining Term estrogen receptor
UniProt ID E7FJU2_MOUSE
Name Estrogen receptor 1 (Alpha), isoform CRA_b
Estrogen receptor alpha
Gene Names Esr1
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0008209 androgen metabolic process BP
GO:0060745 mammary gland branching involved in pregnancy BP
GO:0001547 antral ovarian follicle growth BP
GO:0060523 prostate epithelial cord elongation BP
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis BP
GO:0060068 vagina development BP
GO:0002064 epithelial cell development BP
GO:0043565 sequence-specific DNA binding MF
GO:0048146 positive regulation of fibroblast proliferation BP
GO:0003682 chromatin binding MF
GO:0008270 zinc ion binding MF
GO:0060687 regulation of branching involved in prostate gland morphogenesis BP
GO:0060065 uterus development BP
GO:0006351 transcription, DNA-dependent BP
GO:0071391 cellular response to estrogen stimulus BP
GO:0003700 sequence-specific DNA binding transcription factor activity MF
GO:0005634 nucleus CC
GO:0060749 mammary gland alveolus development BP
GO:0045944 positive regulation of transcription from RNA polymerase II promoter BP
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation BP

Sequence

>gi|6679695|ref|NP_031982.1| estrogen receptor [Mus musculus]
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPTVFNYPEGAAYEFNAAAAAAA
AASAPVYGQSGIAYGPGSEAAAFSANSLGAFPQLNSVSPSPLMLLHPPPQLSPFLHPHGQQVPYYLENEP
SAYAVRDTGPPAFYRSNSDNRRQNGRERLSSSNEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCK
AFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEG
RNEMGASGDMRAANLWPSPLVIKHTKKNSPALSLTADQMVSALLDAEPPMIYSEYDPSRPFSEASMMGLL
TNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGK
CVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTL
IHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAPASRM
GVPPEEPSQTQLATTSSTSAHSLQTYYIPPEAEGFPNTI

Options for BLAST

Database:

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Database Cross Reference

Ensembl Gene
UniGene Mm.9213
Mm.463262
PDB
RefSeq NP_031982.1
Pfam PF00105
PF00104
PF12743
PF02159