Text mining Term | calpain inhibitor |
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UniProt ID | ICAL_RAT |
Name |
Calpain inhibitor Calpastatin |
Gene Names |
Cast
|
Taxonomy | Rattus norvegicus |
Function |
Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. |
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Subcellular location |
GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity | MF |
>gi|76159291|ref|NP_001028888.1| calpastatin isoform c [Rattus norvegicus] MSRPGPKPAASSRPRRGAAASHTQEHVNEKNIGSSSKPAEKKGSDEVTASSAATGTSPRMSTTGAKAVKI ESEKSQSSEPPVIHEKKPKGKPKEGSETKFQDAPSADGESVAGGVTVATASDKVVVKSGVNAALDDLIDT LGECEDTNKDDPPYTGPVVLDPMDSTYLEALGIKEGTIPPEYRKLLEKNEAITGPLPDSPKPMGIDHAID ALSSDFTCSSPTGKQTEKEKSTGESSKAQSAGVTRSAVPPQEKKRKVEEEVMNDQALQALSDSLGTRQPD PQSHLRQAKQVKEAKAKEERQEKCGEDEDTVPAEYRLKPAKDKDGKPLLPEPEETSKCLSESELIGELSA DFVQPTYQEKPSMPAAKIKKGVVPDDAVETLARSLGTRKEDPEDEKSLVDKVKEKAKEEDHEKLGEKEET IPPDYRLEIVKDKDGKPLLPKEAEEQLPPLSDDFLLDALSQDFSSPANILSLGFEDAKLSAAVSETVSQV PAPSNHTAAPPPGTERRDKELDDALDELSDSLGQRQPDPDENKPLDDKVKEKIKAEHSEKLGERDDTIPP EYRHLLDNDGKDKPEKPLTKNTEKPGQDQDPIDALSEDLDSCPPTTETSQNTTKEKGKKTSSSKASKNEE KTKDSSKKTEEVPKPKVDEDAT |
Ensembl Gene |
ENSRNOT00000062054 |
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UniGene |
Rn.17481 |
PDB |
3BOW 3DF0 |
RefSeq |
NP_001028887.1 NP_001028888.1 NP_445747.2 |
Pfam |
PF00748 |