cholecystokinin

General Information (Source: NCBI Gene,UniProt)

Text mining Term cholecystokinin
UniProt ID CCKN_MOUSE
Name Cholecystokinin
CCK12
CCK33
Cholecystokinin-33
CCK8
Cholecystokinin-12
Cholecystokinin-8
CCK
Gene Names Cck
Taxonomy Mus musculus

General annotation

Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Subcellular location Secreted.

Gene Ontology

GO:0001764 neuron migration BP
GO:0003677 DNA binding MF
GO:0042755 eating behavior BP
GO:0007409 axonogenesis BP
GO:0005184 neuropeptide hormone activity MF
GO:0030424 axon CC
GO:0005576 extracellular region CC

Sequence

>gi|13624301|ref|NP_112438.1| cholecystokinin preproprotein [Mus musculus]
MKSGVCLCVVMAVLAAGALAQPVVPAEATDPVEQRAQEAPRRQLRAVLRTDGEPRARLGALLARYIQQVR
KAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDFGRRSAEDYEYPS

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Database Cross Reference

Ensembl Gene ENSMUST00000035120
UniGene Mm.2619
PDB
RefSeq NP_112438.1
Pfam PF00918