| Text mining Term | Vesicular glutamate transporter 2 |
|---|---|
| UniProt ID | VGLU2_RAT |
| Name |
Differentiation-associated BNPI Vesicular glutamate transporter 2 Solute carrier family 17 member 6 VGluT2 Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter |
| Gene Names |
Slc17a6
|
| Taxonomy | Rattus norvegicus |
| Function |
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate. |
|---|---|
| Subcellular location |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome. |
| GO:0016021 | integral to membrane | CC |
| GO:0001504 | neurotransmitter uptake | BP |
| GO:0015293 | symporter activity | MF |
| GO:0019717 | synaptosome | CC |
| GO:0030672 | synaptic vesicle membrane | CC |
| GO:0005313 | L-glutamate transmembrane transporter activity | MF |
| GO:0030054 | cell junction | CC |
| GO:0006814 | sodium ion transport | BP |
| GO:0005769 | early endosome | CC |
>gi|16758166|ref|NP_445879.1| vesicular glutamate transporter 2 [Rattus norvegicus] MESVKQRILAPGKEGIKNFAGKSLGQIYRVLEKKQDNRETIELTEDGKPLEVPEKKAPLCDCTCFGLPRR YIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQI PGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLE RSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERR YIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGM LSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAV GFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGG VIFYALFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATSQENGGWPNGWEK KEEFVQESAQDAYSYKDRDDYS |
| Ensembl Gene | |
|---|---|
| UniGene |
Rn.19372 |
| PDB | |
| RefSeq |
NP_445879.1 |
| Pfam |
PF07690 |