metabotropic glutamate receptor 4

General Information (Source: NCBI Gene,UniProt)

Text mining Term metabotropic glutamate receptor 4
UniProt ID GRM4_MOUSE
Name Metabotropic glutamate receptor 4
mGluR4
Gene Names Grm4
Taxonomy Mus musculus

General annotation

Function Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity (By similarity).
Subcellular location Cell membrane; Multi-pass membrane protein.

Gene Ontology

GO:0016021 integral to membrane CC
GO:0001642 group III metabotropic glutamate receptor activity MF
GO:0005886 plasma membrane CC
GO:0007268 synaptic transmission BP
GO:0007612 learning BP

Sequence

>gi|62945392|ref|NP_001013403.1| metabotropic glutamate receptor 4 precursor [Mus musculus]
MSGKGGWAWWWARLPLCLLLSLYGSWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKACGEL
KKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGG
PPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMV
DIVRALKWNYVSTLASEGSYGESGVEAFIQKSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARA
IIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRTSVRGFDRYFSS
RTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQRRNGSAEYK
VIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCWHCEPCTGYQYQVDRYTCKTC
PYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIAATLFVVVTFVRYNDTPIVKASGRELSYVLL
AGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQL
AITFVLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVY
AIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKVTSEALPVEFSPPLLAHN

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000088073
ENSMUST00000163112
UniGene Mm.358940
PDB
RefSeq NP_001013403.1
Pfam PF01094
PF07562
PF00003