vesicular GABA transporter

General Information (Source: NCBI Gene,UniProt)

Text mining Term vesicular GABA transporter
UniProt ID VIAAT_RAT
Name Solute carrier family 32 member 1
GABA and glycine transporter
Vesicular GABA transporter
Vesicular inhibitory amino acid transporter
rGVAT
Gene Names Slc32a1
Taxonomy Rattus norvegicus

General annotation

Function Involved in the uptake of GABA and glycine into the synaptic vesicles.
Subcellular location Cytoplasmic vesicle membrane; Multi-pass membrane protein.

Gene Ontology

GO:0006836 neurotransmitter transport BP
GO:0015187 glycine transmembrane transporter activity MF
GO:0060077 inhibitory synapse CC
GO:0030659 cytoplasmic vesicle membrane CC
GO:0016021 integral to membrane CC
GO:0008021 synaptic vesicle CC
GO:0007568 aging BP

Sequence

>gi|13929106|ref|NP_113970.1| vesicular inhibitory amino acid transporter [Rattus norvegicus]
MATLLRSKLTNVATSVSNKSQAKVSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQMDILKSEGEPC
GDEGAEPPVEGDIHYQRGGAPLPPSGSKDQAVGAGGEFGGHDKPKITAWEAGWNVTNAIQGMFVLGLPYA
ILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQ
IIELVMTCILYVVVSGNLMYNSFPGLPVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINIL
VIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVL
KGLFALVAYLTWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPA
CYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQV
FFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED

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Database Cross Reference

Ensembl Gene ENSRNOT00000020720
UniGene Rn.10846
PDB
RefSeq NP_113970.1
XP_002726335.1
Pfam PF01490