arginine vasopressin

General Information (Source: NCBI Gene,UniProt)

Text mining Term arginine vasopressin
UniProt ID NEU2_RAT
Name Arg-vasopressin
Copeptin
Neurophysin-I
Vasopressin-neurophysin 2-copeptin
AVP-NPII
Neurophysin 2
Gene Names Avp
Taxonomy Rattus norvegicus

General annotation

Function Neurophysin 2 specifically binds vasopressin. Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels.
Subcellular location Secreted.

Gene Ontology

GO:0030141 secretory granule CC
GO:0050891 multicellular organismal water homeostasis BP
GO:0003084 positive regulation of systemic arterial blood pressure BP
GO:0030307 positive regulation of cell growth BP
GO:0007626 locomotory behavior BP
GO:0005615 extracellular space CC
GO:0005185 neurohypophyseal hormone activity MF
GO:0042711 maternal behavior BP
GO:0051970 negative regulation of transmission of nerve impulse BP
GO:0031894 V1A vasopressin receptor binding MF
GO:0002125 maternal aggressive behavior BP
GO:0042310 vasoconstriction BP
GO:0001659 temperature homeostasis BP
GO:0045907 positive regulation of vasoconstriction BP
GO:0007625 grooming behavior BP
GO:0043084 penile erection BP
GO:0008284 positive regulation of cell proliferation BP
GO:0014049 positive regulation of glutamate secretion BP
GO:0006939 smooth muscle contraction BP
GO:0042538 hyperosmotic salinity response BP
GO:0031895 V1B vasopressin receptor binding MF
GO:0045471 response to ethanol BP
GO:0007621 negative regulation of female receptivity BP
GO:0031394 positive regulation of prostaglandin biosynthetic process BP
GO:0035813 regulation of renal sodium excretion BP
GO:0035176 social behavior BP
GO:0007204 elevation of cytosolic calcium ion concentration BP
GO:0035094 response to nicotine BP
GO:0032849 positive regulation of cellular pH reduction BP
GO:0031896 V2 vasopressin receptor binding MF
GO:0030425 dendrite CC

Sequence

>gi|291327518|ref|NP_058688.2| vasopressin-neurophysin 2-copeptin preproprotein [Rattus norvegicus]
MLAMMLNTTLSACFLSLLALTSACYFQNCPRGGKRATSDMELRQCLPCGPGGKGRCFGPSICCADELGCF
LGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCSDESCVAEPECREGFFRLTRAREQSNATQLD
GPARELLLRLVQLAGTQESVDSAKPRVY

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSRNOT00000028833
UniGene Rn.9976
PDB
RefSeq NP_058688.2
Pfam PF00184
PF00220