factor A

General Information (Source: NCBI Gene,UniProt)

Text mining Term factor A
UniProt ID TF3A_MOUSE
Name Transcription factor IIIA
TFIIIA
Gene Names Gtf3a
Taxonomy Mus musculus

General annotation

Function Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes (By similarity).
Subcellular location Nucleus (By similarity).

Gene Ontology

GO:0008270 zinc ion binding MF
GO:0006351 transcription, DNA-dependent BP
GO:0003723 RNA binding MF
GO:0003677 DNA binding MF
GO:0005634 nucleus CC
GO:0006355 regulation of transcription, DNA-dependent BP

Sequence

>gi|167466248|ref|NP_079928.2| transcription factor IIIA [Mus musculus]
MEPRVSVAEAVSSLTIADAFVGACEGPAPPRPALPSRFICSFPDCSASYNKAWKLDAHLCKHTGERPFVC
DYEGCGKAFIRDYHLSRHVLIHTGEKPFVCADDGCNQKFNTKSNLKKHIERKHGNPQKQYVCSYEGCKKA
FKKHQQLRTHQCQHTSEPLFRCTHEGCGKHFASPSRLKRHGKVHEGYLCQKGCSFMGKTWTELLKHMREA
HKEDITCNVCQRMFKRRDYLKQHMKTHAPERDVYRCPRQGCGRTYTTVFNLQSHILSFHEEKRPFVCEHA
GCGKTFAMKQSLMRHSVVHDPDKKRMKLKVRAPRERRSLASRLSGYFPPKRKQEPDYSLPNASAESSSSP
EAQLPPPAALLTVC

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000016647
UniGene Mm.358698
PDB
RefSeq NP_079928.2
Pfam PF00096