factor A

General Information (Source: NCBI Gene,UniProt)

Text mining Term factor A
UniProt ID TF3A_RAT
Name TFIIIA
Transcription factor IIIA
Gene Names Gtf3a
Taxonomy Rattus norvegicus

General annotation

Function Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes (By similarity).
Subcellular location Nucleus (By similarity).

Gene Ontology

GO:0003677 DNA binding MF
GO:0005634 nucleus CC
GO:0006351 transcription, DNA-dependent BP
GO:0003723 RNA binding MF
GO:0008270 zinc ion binding MF
GO:0003700 sequence-specific DNA binding transcription factor activity MF

Sequence

>gi|166064004|ref|NP_001107042.1| transcription factor IIIA [Rattus norvegicus]
MEPRVSVAEAVSSLTIADAFVRACVGPAPPRPALPSRFICSFPDCSASYNKAWKLDAHLCKHTGERPFVC
DYEGCGKAFIRDYHLSRHILIHTGEKPFVCADNGCNQKFSTKSNLKKHIERKHENPQKQYVCNFEGCKKA
FKKHQQLRTHQCQHTNEPLFRCTHEGCGKHFASPSRLKRHGKVHEGYLCQKGCSFVGKTWTELLKHTREA
HKEEVTCTVCQKMFKRKDHLKQHMKTHAPERDVYRCPREGCARTYTTVFNLQSHILSFHEEKRPFVCEHA
GCGKTFAMKQSLMRHSVVHDPDKKRMKLKVRPPRERRSLASRLSGYVPPKGKQEPDCSLPNSTESSSSPE
ATMLAPAALLTVH

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.195324
PDB
RefSeq NP_001107042.1
Pfam PF00096