| Text mining Term | GABA transaminase |
|---|---|
| UniProt ID | GABT_MOUSE |
| Name |
L-AIBAT GABA-T GABA aminotransferase (S)-3-amino-2-methylpropionate transaminase Gamma-amino-N-butyrate transaminase GABA transaminase GABA-AT 4-aminobutyrate aminotransferase, mitochondrial |
| Gene Names |
Abat
Synonyms:Gabat |
| Taxonomy | Mus musculus |
| Function |
Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (By similarity). |
|---|---|
| Subcellular location |
Mitochondrion matrix (By similarity). |
| GO:0005759 | mitochondrial matrix | CC |
| GO:0042803 | protein homodimerization activity | MF |
| GO:0047298 | (S)-3-amino-2-methylpropionate transaminase activity | MF |
| GO:0048148 | behavioral response to cocaine | BP |
| GO:0030170 | pyridoxal phosphate binding | MF |
| GO:0042135 | neurotransmitter catabolic process | BP |
| GO:0032145 | succinate-semialdehyde dehydrogenase binding | MF |
| GO:0003867 | 4-aminobutyrate transaminase activity | MF |
| GO:0009448 | gamma-aminobutyric acid metabolic process | BP |
| GO:0032144 | 4-aminobutyrate transaminase complex | CC |
>gi|37202121|ref|NP_766549.2| 4-aminobutyrate aminotransferase, mitochondrial isoform 1 precursor [Mus musculus] MAFLLITRRLACSSQKNLHLFIPGSRYISQAAAKVDIEFDYDGPLMKTEVPGPRSKELMKQLNTIQNAEA VHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYNHPALAKLVQQPQNASTFINRPALGILPPENFV DKLQESLMSVAPRGMSQLITMACGSCSNENAFKTIFMWYRSKERGQRGFSKEELETCMVNQSPGCPDYSI LSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFTTDNQQEEARCLEEVEDLIVKY RKKKRTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPA DVMTFSKKMMTGGFFHKEEFRPSAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNVARVGKTLLTGLL DLQAQYPQFISRVRGRGTFCSFDTPDEAIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLS IFSGILADFK |
| Ensembl Gene |
ENSMUST00000115839 ENSMUST00000065987 |
|---|---|
| UniGene |
Mm.259315 |
| PDB | |
| RefSeq |
NP_001164449.1 NP_766549.2 |
| Pfam |
PF00202 |