brain derived neurotrophic factor

General Information (Source: NCBI Gene,UniProt)

Text mining Term brain derived neurotrophic factor
UniProt ID A2AII2_MOUSE
Name Uncharacterized protein
Brain derived neurotrophic factor
Gene Names Bdnf
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0001657 ureteric bud development BP
GO:0021675 nerve development BP
GO:0014047 glutamate secretion BP
GO:0007412 axon target recognition BP
GO:0008038 neuron recognition BP
GO:0048839 inner ear development BP
GO:0007411 axon guidance BP
GO:0042596 fear response BP
GO:0006916 anti-apoptosis BP
GO:0048167 regulation of synaptic plasticity BP
GO:0016023 cytoplasmic membrane-bounded vesicle CC
GO:0046668 regulation of retinal cell programmed cell death BP
GO:0043524 negative regulation of neuron apoptosis BP
GO:0007631 feeding behavior BP
GO:0016358 dendrite development BP
GO:0007611 learning or memory BP
GO:0042493 response to drug BP
GO:0019222 regulation of metabolic process BP
GO:0045666 positive regulation of neuron differentiation BP
GO:0007406 negative regulation of neuroblast proliferation BP
GO:0008083 growth factor activity MF

Sequence

>gi|114326463|ref|NP_031566.4| brain-derived neurotrophic factor isoform 1 precursor [Mus musculus]
MFHQVRRVMTILFLTMVISYFGCMKAAPMKEVNVHGQGNLAYPGVRTHGTLESVNGPRAGSRGLTTTSLA
DTFEHVIEELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHS
DPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGID
KRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000053317
UniGene Mm.1442
PDB
RefSeq NP_031566.4
Pfam PF00243