glial fibrillary acidic protein

General Information (Source: NCBI Gene,UniProt)

Text mining Term glial fibrillary acidic protein
UniProt ID GFAP_RAT
Name Glial fibrillary acidic protein
GFAP
Gene Names Gfap
Taxonomy Rattus norvegicus

General annotation

Function GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Subcellular location Cytoplasm (By similarity). Note=Associated with intermediate filaments (By similarity).

Gene Ontology

GO:0009611 response to wounding BP
GO:0005882 intermediate filament CC
GO:0005200 structural constituent of cytoskeleton MF
GO:0005737 cytoplasm CC
GO:0019900 kinase binding MF
GO:0005178 integrin binding MF

Sequence

>gi|158186732|ref|NP_058705.2| glial fibrillary acidic protein [Rattus norvegicus]
MERRRITSARRSYASSETMVRGHGPTRHLGTIPRLSLSRMTPPLPARVDFSLAGALNAGFKETRASERAE
MMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTTNSARLEVERD
NLTQDLGTLRQKLQDETNLRLEAENNLAVYRQEADEATLARVDLERKVESLEEEIQFLRKIHEEEVRELQ
EQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDVASRNAELLRQAKHEA
NDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDL
LNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIK
ESKQEHKDVM

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSRNOT00000034401
UniGene Rn.91512
PDB
RefSeq NP_058705.2
Pfam PF00038