leptin

General Information (Source: NCBI Gene,UniProt)

Text mining Term leptin
UniProt ID Q544U0_MOUSE
Name Leptin
Leptin, isoform CRA_a
Gene Names Lep
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0008083 growth factor activity MF
GO:0042445 hormone metabolic process BP
GO:0030300 regulation of intestinal cholesterol absorption BP
GO:0045639 positive regulation of myeloid cell differentiation BP
GO:0006111 regulation of gluconeogenesis BP
GO:0060612 adipose tissue development BP
GO:0030073 insulin secretion BP
GO:0021954 central nervous system neuron development BP
GO:0008206 bile acid metabolic process BP
GO:0032868 response to insulin stimulus BP
GO:0050810 regulation of steroid biosynthetic process BP
GO:0042755 eating behavior BP
GO:0002021 response to dietary excess BP
GO:0008203 cholesterol metabolic process BP
GO:0050796 regulation of insulin secretion BP
GO:0005615 extracellular space CC
GO:0006006 glucose metabolic process BP

Sequence

>gi|6678678|ref|NP_032519.1| leptin precursor [Mus musculus]
MCWRPLCRFLWLWSYLSYVQAVPIQKVQDDTKTLIKTIVTRINDISHTQSVSAKQRVTGLDFIPGLHPIL
SLSKMDQTLAVYQQVLTSLPSQNVLQIANDLENLRDLLHLLAFSKSCSLPQTSGLQKPESLDGVLEASLY
STEVVALSRLQGSLQDILQQLDVSPEC

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Mm.277072
PDB
RefSeq NP_032519.1
Pfam PF02024