beta 2 microglobulin

General Information (Source: NCBI Gene,UniProt)

Text mining Term beta 2 microglobulin
UniProt ID Q91XJ8_MOUSE
Name Uncharacterized protein
Beta-2 microglobulin
Gene Names B2m
Taxonomy Mus musculus

General annotation

Function Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). ----------------------------------------------------------------------- Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms Distributed under the Creative Commons Attribution-NoDerivs License -----------------------------------------------------------------------
Subcellular location

Gene Ontology

GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent BP
GO:0006955 immune response BP
GO:0042026 protein refolding BP
GO:0005515 protein binding MF
GO:0001916 positive regulation of T cell mediated cytotoxicity BP
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I BP
GO:0009897 external side of plasma membrane CC
GO:0002237 response to molecule of bacterial origin BP
GO:0042612 MHC class I protein complex CC
GO:0006968 cellular defense response BP
GO:0033077 T cell differentiation in thymus BP

Sequence

>gi|31981890|ref|NP_033865.2| beta-2-microglobulin precursor [Mus musculus]
MARSVTLVFLVLVSLTGLYAIQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIEIQMLKNGKKIPKVE
MSDMSFSKDWSFYILAHTEFTPTETDTYACRVKHASMAEPKTVYWDRDM

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000102476
UniGene Mm.163
PDB 3ARB
3QUZ
2QRI
3ARD
3E6F
2QRT
3ARF
2QRS
3E6H
3O9W
3QUY
3O8X
3RUG
3MA7
3ARG
3QUX
3ARE
RefSeq NP_033865.2
Pfam PF07654