galectin 1

General Information (Source: NCBI Gene,UniProt)

Text mining Term galectin 1
UniProt ID LEG1_RAT
Name 14 kDa lectin
Lectin galactoside-binding soluble 1
Galaptin
S-Lac lectin 1
RL 14.5
Gal-1
Beta-galactoside-binding lectin L-14-I
Galectin-1
Lactose-binding lectin 1
Gene Names Lgals1
Taxonomy Rattus norvegicus

General annotation

Function May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates (By similarity).
Subcellular location Secreted, extracellular space, extracellular matrix (By similarity).

Gene Ontology

GO:0010812 negative regulation of cell-substrate adhesion BP
GO:0005578 proteinaceous extracellular matrix CC
GO:0071407 cellular response to organic cyclic compound BP
GO:0071333 cellular response to glucose stimulus BP
GO:0001948 glycoprotein binding MF
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0033555 multicellular organismal response to stress BP
GO:0042493 response to drug BP
GO:0034120 positive regulation of erythrocyte aggregation BP
GO:0009986 cell surface CC
GO:0030395 lactose binding MF
GO:0016936 galactoside binding MF
GO:0042803 protein homodimerization activity MF
GO:0048678 response to axon injury BP
GO:0043236 laminin binding MF
GO:0010977 negative regulation of neuron projection development BP

Sequence

>gi|9845261|ref|NP_063969.1| galectin-1 [Rattus norvegicus]
MACGLVASNLNLKPGECLKVRGELAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDDGTWG
TEQRETAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE

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Database Cross Reference

Ensembl Gene
UniGene Rn.57
PDB 3M2M
RefSeq NP_063969.1
Pfam PF00337