apolipoprotein E

General Information (Source: NCBI Gene,UniProt)

Text mining Term apolipoprotein E
UniProt ID Q3TXU4_MOUSE
Name Apolipoprotein E, isoform CRA_h
Gene Names Apoe
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0071813 lipoprotein particle binding MF
GO:0010468 regulation of gene expression BP
GO:0042158 lipoprotein biosynthetic process BP
GO:0051651 maintenance of location in cell BP
GO:0048844 artery morphogenesis BP
GO:0042159 lipoprotein catabolic process BP
GO:0006874 cellular calcium ion homeostasis BP
GO:0033344 cholesterol efflux BP
GO:0042311 vasodilation BP
GO:0017127 cholesterol transporter activity MF
GO:0006707 cholesterol catabolic process BP
GO:0042632 cholesterol homeostasis BP
GO:0006979 response to oxidative stress BP
GO:0002021 response to dietary excess BP

Sequence

>gi|163644329|ref|NP_033826.2| apolipoprotein E precursor [Mus musculus]
MKALWAVLLVTLLTGCLAEGEPEVTDQLEWQSNQPWEQALNRFWDYLRWVQTLSDQVQEELQSSQVTQEL
TALMEDTMTEVKAYKKELEEQLGPVAEETRARLGKEVQAAQARLGADMEDLRNRLGQYRNEVHTMLGQST
EEIRARLSTHLRKMRKRLMRDAEDLQKRLAVYKAGAREGAERGVSAIRERLGPLVEQGRQRTANLGAGAA
QPLRDRAQAFGDRIRGRLEEVGNQARDRLEEVREHMEEVRSKMEEQTQQIRLQAEIFQARLKGWFEPIVE
DMHRQWANLMEKIQASVATNPIITPVAQENQ

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Mm.305152
PDB
RefSeq NP_033826.2
Pfam PF01442