Text mining Term | Pit 1 |
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UniProt ID | S20A1_MOUSE |
Name |
Sodium-dependent phosphate transporter 1 Gibbon ape leukemia virus receptor 1 PiT-1 Leukemia virus receptor 1 homolog GLVR-1 Solute carrier family 20 member 1 Phosphate transporter 1 |
Gene Names |
Slc20a1
|
Taxonomy | Mus musculus |
Function |
Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor but do not confer infection susceptibility to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B). |
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Subcellular location |
Membrane; Multi-pass membrane protein (By similarity). |
GO:0005315 | inorganic phosphate transmembrane transporter activity | MF |
GO:0004872 | receptor activity | MF |
GO:0005886 | plasma membrane | CC |
GO:0016021 | integral to membrane | CC |
>gi|227430320|ref|NP_001153065.1| sodium-dependent phosphate transporter 1 isoform 2 [Mus musculus] MESTVATITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILA SIFETVGSALLGAKVSETIRNGLIDVELYNETQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGA TIGFSLVANGQKGVKWSELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKADPVPNGLRALPIFYACTI GINLFSIMYTGAPWLKSPRRWLACIHFRRLQASVC |
Ensembl Gene |
ENSMUST00000110315 ENSMUST00000028880 |
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UniGene |
Mm.272675 |
PDB | |
RefSeq |
NP_001153065.1 NP_056562.1 |
Pfam |
PF01384 |