bone morphogenetic protein 2

General Information (Source: NCBI Gene,UniProt)

Text mining Term bone morphogenetic protein 2
UniProt ID BMP2_RAT
Name BMP-2
BMP-2A
Bone morphogenetic protein 2A
Bone morphogenetic protein 2
Gene Names Bmp2
Taxonomy Rattus norvegicus

General annotation

Function Induces cartilage and bone formation.
Subcellular location Secreted (By similarity).

Gene Ontology

GO:0008083 growth factor activity MF
GO:0045944 positive regulation of transcription from RNA polymerase II promoter BP
GO:0005737 cytoplasm CC
GO:0042698 ovulation cycle BP
GO:0043234 protein complex CC
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation BP
GO:0040007 growth BP
GO:0005615 extracellular space CC
GO:0031988 membrane-bounded vesicle CC
GO:0009612 response to mechanical stimulus BP
GO:0060395 SMAD protein signal transduction BP
GO:0051216 cartilage development BP
GO:0005125 cytokine activity MF
GO:0042803 protein homodimerization activity MF
GO:0019904 protein domain specific binding MF
GO:0032526 response to retinoic acid BP

Sequence

>gi|8392990|ref|NP_058874.1| bone morphogenetic protein 2 precursor [Rattus norvegicus]
MVAGTRCLLVLLLPQVLLGGAAGLIPELGRKKFAGASRPLSRPSEDVLSEFELRLLSMFGLKQRPTPSKD
VVVPPYMLDLYRRHSGQPGALAPDHRLERAASRANTVLSFHHEEAIEELSEMSGKTSRRFFFNLSSVPTD
EFLTSAELQIFREQMQEALGNSSFQHRINIYEIIKPATASSKFPVTRLLDTRLVTQNTSQWESFDVTPAV
MRWTAQGHTNHGFVVEVAHLEEKPGVSKRHVRISRSLHQDEHSWSQVRPLLVTFGHDGKGHPLHKREKRQ
AKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVN
SKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.90931
PDB
RefSeq NP_058874.1
Pfam PF00688
PF00019